Which cancer has increased risk in women with PCOS?

Women with PCOS are at increased risk of endometrial cancer. Chronic unopposed estrogen exposure is probably the proximate risk factor. This may be confounded by obesity, hypertension, and diabetes, which are known correlates of endometrial cancer risk. It is imperative to screen all women with PCOS, even those who are considered too young to develop endometrial hyperplasia and carcinoma.